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Basophil

A leukocyte with basophilic granules easily stained by basic stains.basophil

(Science: haematology) Mammalian granulocyte with large heterochromatic basophilic granules that contain histamine bound to a protein and heparin like mucopolysaccharide matrix. They are not phagocytic. Very similar to mast cells though it is not clear whether they have common lineage. A type of granulocyte (white blood cell) that in synthesised in the bone marrow.


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Immunology: Th1/Th2 vs cellular/humoral responses

... harmless allergens, whilst atopic persons have Th2-deviated (cytokines such as IL4) responses that promote IgE formation. IgE, in turn, binds to basophils and mast cells and when an allergen is bound by its specific IgE, it cross-links the FceRI receptors on surface of the basophil and causes ...

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by biohazard
Tue Nov 02, 2010 9:35 am
 
Forum: Cell Biology
Topic: Immunology: Th1/Th2 vs cellular/humoral responses
Replies: 10
Views: 42907

Composition of white blood cells.

... is the right one!! please help me =) http://www.ivy-rose.co.uk/Topics/Blood_Structure&Functions.htm This link says that basophils are 60-70% of leucocytes, neutrophils 2-4%, eosinophils 0.5%. http://www.funsci.com/fun3_en/blood/blood.htm http://www.ndsu.nodak.edu/instruct/tcolvill/435/granulocytes.htm ...

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by crayonkazuyori
Sat May 16, 2009 4:48 pm
 
Forum: Cell Biology
Topic: Composition of white blood cells.
Replies: 2
Views: 10537

Re: white blood cell

... cells do eat antigens (e.g. neutrophil and macrophage), some other cells secrete enzyme(s) or other protein substance(s) to kill pathogens (e.g. basophil, acidophil), another cell produces antibody (B-cell), et. etc. Maybe this is what Arthurius meant by "not always endocrine" --> ...

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by DoctorStein
Fri May 30, 2008 10:13 am
 
Forum: Human Biology
Topic: white blood cell
Replies: 9
Views: 7413

Basophils vs. Mastocytes

... owned by other cells. Those scientists trace it in order to get mast cell "ancestor", which bring the marker. The result showed that basophil also bring that marker, thus so far it is conluded that mast cell is derived from the same precursor as basophil. I never heard of "mastoblast" ...

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by Dr.Stein
Tue Mar 06, 2007 5:30 am
 
Forum: Physiology
Topic: Basophils vs. Mastocytes
Replies: 4
Views: 6297

Basophils vs. Mastocytes

Yes, both basophils and mast cells take part in allergy and hypersensitivity. It is stated that mast cell is derived from basophil, similar to how macrophage is derived from monocytes: basophil and monocytes circulates in peripheral ...

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by Dr.Stein
Thu Feb 01, 2007 10:12 am
 
Forum: Physiology
Topic: Basophils vs. Mastocytes
Replies: 4
Views: 6297
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