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Base-stacking

Base-stacking

a clustering of dna or rna bases in which the rings lie on top of each other.


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Ligase reaction problem

Dear Friends, I uploded an image you can see below. Here, I want to ask whether it is enough base lenght for ligase reaction via thermostable ligase in 63 C (Protocol: 5 cycle at 95 C-30 s and 63 C-4 min) I think I take cross reaction because of this dimer but I am not ...

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by Molbio34
Thu Feb 26, 2015 8:27 am
 
Forum: Molecular Biology
Topic: Ligase reaction problem
Replies: 0
Views: 323

Re: Any ideas for vaccine development or anti-viral drugs???

... were assayed for the ability to inhibit EBOV infection in cell culture and in a mouse model of lethal EBOV infection. A 22-mer P-PMO designed to base pair with the translation start site region of EBOV VP35 positive-sense RNA generated sequence-specific and time- and dose-dependent inhibition ...

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by jonmoulton
Mon Sep 15, 2014 3:04 pm
 
Forum: Cell Biology
Topic: Any ideas for vaccine development or anti-viral drugs???
Replies: 2
Views: 12571

Any ideas for vaccine development or anti-viral drugs???

... has been concentrated in this area, as there are no successful vaccines or drugs available for the control of the disease. So i was wanting to base my write-up on this. Certain drugs target the various replication machinery, could anybody suggest how i should go about this? any other field ...

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by Microbuddy
Mon Sep 15, 2014 7:43 am
 
Forum: Cell Biology
Topic: Any ideas for vaccine development or anti-viral drugs???
Replies: 2
Views: 12571

Re: Humans Natural Habitat/Optimal Environment

... when he is naked and unprotected, the temperature of his surroundings must be 82.4°F (28°C) for his metabolism to be maintained at a minimum base level, and for him to remain in thermal equilibrium.

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by Gannet
Wed Mar 05, 2014 11:31 pm
 
Forum: Evolution
Topic: Humans Natural Habitat/Optimal Environment
Replies: 2
Views: 8978

Polymorphism and Mutation

Just about numbers. A mutation is a change to a single individual that may or may not be propagated. For example a single point mutation where a base is replaced or deleted from a strand of DNA. This may cause the individual some discomfort or problems but is normally isolated to the individual. ...

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by Babybel56
Wed Mar 05, 2014 3:39 am
 
Forum: Molecular Biology
Topic: Polymorphism and Mutation
Replies: 2
Views: 2961
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