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Barlow syndrome

(Science: syndrome) late apical systolic murmur or (so-called mid-late) systolic click, or both, due to massive billowing of the anterior and/or posterior (mural) mitral valvular leaflet into the left atrial cavity (also, floppy valve syndrome); electrocardiographically, ST-T changes in a posteroinferior distribution resembling those of myocardial ischemia often coexist for unknown reasons; rhythm disturbances may coexist with this syndrome without demonstrable pathogenetic relationship.