An example of an autocrine agent is the cytokine interleukin-1 in monocytes. When this is produced in response to external stimuli, it can bind to cell-surface receptors on the same cell that produced it.
Compare: paracrine signaling.
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... that, at 21C, proliferate and differentiate into cardiomyoctes. The signaling system leading to differentiation seems to involve the PI3K-Akt/PKB ... the graduate student discovered that his cells were producing an autocrine factor that was causing the cells to proliferate without differentiating ...
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