Autocrine

... increased the temperature to 35C. The next day, after a night of tricks/treats, the graduate student discovered that his cells were producing an autocrine factor that was causing the cells to proliferate without differentiating and were capable of record rates of motility. The graduate student, ...

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... was conducted using mRNA from dsRNA-treated GRE cells. Because these cells lack all type I interferon genes, the possibility of gene induction by autocrine actions of interferon was eliminated.

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... Abstract Tumor cells act upon, and react to both their proximate and more distant environment, the mechanisms by which this is achieved being both autocrine and paracrine in nature. This interaction, however, takes place not only between adjacent malignant cells, but also non-malignant cells such ...

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... Somatostatin-producing delta cells (3-10%) * Pancreatic polypeptide-containing PP cells (1%) Islets can influence each other through paracrine and autocrine communication, and beta-cells are coupled electrically to beta-cells (but not to other cell-types). The paracrine feedback system of the islets ...

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... are used as therapeutic agents too. Cytokines are polypeptides secreted by a wide variety of cells in response to diverse stimuli, and mediate autocrine, paracrine, or endocrine effects that are often pleiotropic and redundant. Their molecular weight lies between 6 and 70 kd. The cytokines ...

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