Dictionary » A » Autocrine




Of, relating to, or being a substance that acts on surface receptors of the same cell that produced it.


An example of usage is autocrine signaling.

Word origin: "autos" = self.

Compare: paracrine

Related term:

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eosinophil chemotactic factor help

... of signal transport (At first I assumed endocrine, as a mast cell produces the signal and sends it to an area of inflammation, but then I found autocrine, so now I'm unsure.) 4. Name of receptor (enzyme?) 5. Cellular functions associated with signal (stimulates chemotaxis of eosinophils?) 6. ...

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by relamberth
Tue Dec 01, 2009 11:23 pm
Forum: Cell Biology
Topic: eosinophil chemotactic factor help
Replies: 2
Views: 1982

Hard Advanced Cell Biology Question

... increased the temperature to 35C. The next day, after a night of tricks/treats, the graduate student discovered that his cells were producing an autocrine factor that was causing the cells to proliferate without differentiating and were capable of record rates of motility. The graduate student, ...

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by superscience
Mon Dec 03, 2007 11:41 pm
Forum: Cell Biology
Topic: Hard Advanced Cell Biology Question
Replies: 0
Views: 3130

how to detect dsRNA ?

... was conducted using mRNA from dsRNA-treated GRE cells. Because these cells lack all type I interferon genes, the possibility of gene induction by autocrine actions of interferon was eliminated.

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by dipjyoti
Sun Feb 18, 2007 10:47 am
Forum: Molecular Biology
Topic: how to detect dsRNA ?
Replies: 6
Views: 5878

The Fiber Disease

... Abstract Tumor cells act upon, and react to both their proximate and more distant environment, the mechanisms by which this is achieved being both autocrine and paracrine in nature. This interaction, however, takes place not only between adjacent malignant cells, but also non-malignant cells such ...

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by London
Wed Dec 06, 2006 1:25 am
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 6242780

The Fiber Disease

... are used as therapeutic agents too. Cytokines are polypeptides secreted by a wide variety of cells in response to diverse stimuli, and mediate autocrine, paracrine, or endocrine effects that are often pleiotropic and redundant. Their molecular weight lies between 6 and 70 kd. The cytokines ...

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by Skytroll
Sun Sep 10, 2006 7:16 pm
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 6242780

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