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Associated macrophage

Associated macrophage

a mature macrophage in an active metabolic state that is cytotoxic to tumour/target cells, usually following exposure to certain cytokines.

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Hi everyone ! I need some help. I would like to overexpress a gene (zfp36) in bone marrow derived-macrophages culture (BMDM). I started my PhD few days ago and I don't have a lot of informations about this technical procedure. So I ask you some questions: - Do you have some ...

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by aureliegineste
Wed Sep 04, 2013 7:48 am
Forum: Molecular Biology
Topic: Overexpression
Replies: 2
Views: 2981

Bio Research Paper Writing

... an noninfected individuals. Immune System Aging Immune senesence is associated with changes in the old as compared with the young. Notably, there ... CD28 marker; when CD28 isn’t expressed, antigen-presenting cells like macrophages no longer recognise the T cell and thus aren’t able to alert ...

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by NathanielZhu
Thu Apr 04, 2013 2:25 am
Forum: General Discussion
Topic: Bio Research Paper Writing
Replies: 3
Views: 18507

Nuclei fills the whole cell

... They can uptake GFP proteins from other tissue. People think they might be drosophila kidney, but I dont believe. I think they might be similar to macrophage. Most interestingly, lately I found that, in those cells from the aged adult flies (only from aged fly, but not from young fly), the whole ...

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by genomy
Mon Mar 05, 2012 7:36 pm
Forum: Cell Biology
Topic: Nuclei fills the whole cell
Replies: 0
Views: 1284

Does Langerhan cell in epidermis change to macrophage?

Langerhans cells are antigen presenting cells and macrophages are phagocytes. They both act in the immune responds. Macrophages are found in the tissue where monocytes(lymphocytes) in the blood, slips it way through into the tissue and differentiate into macrophages. Langerhans cells are found in th...

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by AUY11345303
Tue Dec 20, 2011 3:58 pm
Forum: Human Biology
Topic: Does Langerhan cell in epidermis change to macrophage?
Replies: 0
Views: 1514

Can you recommend a vector?

... (as detected by western and qPCR) of the transgene for 8-12 cell passages, but then the CMV becomes silenced. We are working in Raw 267.4 cells, a macrophage line which are apparently notorious for this. So far i am looking for a human promoter within the plasmid which is inducible by the addition ...

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by JimmyTee
Wed Jun 15, 2011 3:17 pm
Forum: Molecular Biology
Topic: Can you recommend a vector?
Replies: 0
Views: 1777
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