Dictionary » A » Apoptosis

Apoptosis

Apoptosis

(Science: cell biology) Programmed cell death as signalled by the nuclei in normally functioning human and animal cells when age or state of cell health and condition dictates.

An active process requiring metabolic activity by the dying cell, often characterised by cleavage of the dna into fragments that give a so called laddering pattern on gels.

cells that die by apoptosis do not usually elicit the inflammatory responses that are associated with necrosis, though the reasons are not clear.

cancerous cells, however, are unable to experience the normal cell transduction or apoptosis-driven natural cell death process.

See: ced mutant, bcl.


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


My “Eureka” moment. A cure for cancer.

... not so much because the cancer cells divide abnormally but because the cancer cells don't die or undergo programmed cell death called "apoptosis" normally and are abnormally immortal. Such normally dividing but abnormally immortal cells would cease dividing if an all-body-tissue ...

See entire post
by PeterDow
Fri Oct 25, 2013 12:14 am
 
Forum: Human Biology
Topic: My “Eureka” moment. A cure for cancer.
Replies: 9
Views: 11435

telomer

... to the strand. but it gets shorter as the replication cycle. as cells age, the telomeres get shorter! shortest telomere or lack of it, signals apoptosis. Cancer cells avoids apoptosis, by synthesis of more and more telomeres which synthesis the ends of chromosomes for the cancer cells...

See entire post
by balamurugan3
Sat Aug 10, 2013 3:52 am
 
Forum: Cell Biology
Topic: telomer
Replies: 2
Views: 1461

Bio Research Paper Writing

... for many cancers (as will be discussed later) targets p53 (tumor supressor pathway) which results in the preservation of the virus by preventing apoptosis of its host cell (DNA-damage-response). Mechanistically, DDR-signaling in mammals are caried out by ATM and ATR which reduces cyclin-dependent ...

See entire post
by NathanielZhu
Thu Apr 04, 2013 2:25 am
 
Forum: General Discussion
Topic: Bio Research Paper Writing
Replies: 1
Views: 12640

Apoptosis in the substantia nigra

... been described in neurons of the aged human brain. However, the cell death process associated with neuronal senescence remains to be elucidated. Apoptosis and autophagic degeneration, two modes of programmed cell death described in embryogenesis and tissue renewal in adult, have been observed ...

See entire post
by MarkHolland
Sat Mar 30, 2013 3:03 pm
 
Forum: Cell Biology
Topic: Apoptosis in the substantia nigra
Replies: 1
Views: 2516

Apoptosis in the substantia nigra

Why is there a higher level of apoptosis in the substantia nigra? Or is there?

See entire post
by ellateflag
Mon Feb 25, 2013 3:05 pm
 
Forum: Cell Biology
Topic: Apoptosis in the substantia nigra
Replies: 1
Views: 2516
View all matching forum results

This page was last modified 21:16, 3 October 2005. This page has been accessed 26,634 times. 
What links here | Related changes | Permanent link