Antigen-antibody complexes

Antigen-antibody complex

The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes immune complex diseases. If the antigen is polyvalent the complex may be insoluble.

immune complexes activate complement through the classical pathway.

See: glomerulonephritis, arthus reaction, type III hypersensitivity.

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