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Antibiotics macrolide

Antibiotics, macrolide

a group of antibiotics containing a macrocyclic lactone ring linked glycosidically to one or more sugar moieties. These antibiotics are produced by certain species of streptomyces. They often inhibit protein synthesis by binding to the 50s subunits of 70s ribosomes.


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Hmmm....differences between bacteria/eukaryote ribosomes?

Some antibiotics take advantage of the ribosomal differences in the cells. For example. Tetracycline ... Binds to the 30S unit of the prokaryote ribosome, mishapes it, and stops transcription. Macrolide - Binds to the 50S unit and stops mRNA movement in the ribosome. These are usually ...

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by EmmVeePee
Mon Jun 27, 2005 8:45 pm
 
Forum: Molecular Biology
Topic: Hmmm....differences between bacteria/eukaryote ribosomes?
Replies: 8
Views: 7169


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