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Androgen

Male sex hormone that is produced in the testes and responsible for typical male sexual characteristics.Any type of male hormone that is involved in expressing secondary male characteristics that would not occur in a female.androgen

(Science: endocrinology) general term for any male sex hormone in vertebrates. Androgens may be used in patients with breast cancer to treat recurrence of the disease.


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Post Finasteride Syndrome - A Silenced AR signal

... a case of a silenced AR signal. Men took propecia ( finasteride 1mg) for hairloss to block DHT. When they stopped, the DHT came flooding back. The androgen receptors were hypersensitive to the DHT, causing a negative autoregulation, effectively silencing the AR signal. What are possible treatment ...

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by SecondAmendment
Thu Feb 09, 2012 8:26 am
 
Forum: Molecular Biology
Topic: Post Finasteride Syndrome - A Silenced AR signal
Replies: 0
Views: 1182

Re:

... to measure this. The genes directly affecting these are not sex-related, but some of the genes that influence the final outcome (e.g. effects on androgen hormon production) are sex-linked. So the answer would be yeas and no, depending on how one interpretes the question :) I just didn't quite ...

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by biohazard
Thu Feb 18, 2010 10:06 am
 
Forum: Genetics
Topic: Question about sexes and gene
Replies: 16
Views: 11952

question about shRNA knocking down

... of 4 can successfully knock down the exgenous protein expression). However, those 3 failed to knock down the endogeous protein in LNCaP cells (an androgen dependent prostate cancer cell line). I thought that maybe the problem of the infection at first, so i repeated the experiment again and got ...

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by zjhzlk
Fri Nov 28, 2008 5:49 pm
 
Forum: Molecular Biology
Topic: question about shRNA knocking down
Replies: 1
Views: 2179

Androgen and oestrogen deficiency or inhibition

Hello all. I would like to discuss this topic of oestrogen and androgen deficiency, and gather some information about it. Besides their effects on sexual characteristics, their development and sexual regulation, what are the other effects of androgens and ...

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by Infotropism
Fri Aug 29, 2008 11:50 pm
 
Forum: Human Biology
Topic: Androgen and oestrogen deficiency or inhibition
Replies: 0
Views: 3045

Estrogen

... figure shows the major metabolic intermediates in the usual synthesis of estrogen, starting with cholesterol, proceeding to pregnenolone (C21), an androgen (C19), and then estrogen (C18). Estrogen has an alcohol functional group at the C3 and C17 positions, and a methyl group at C13. A unique aspect ...

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by chenhongxia
Fri Aug 15, 2008 1:47 am
 
Forum: Physiology
Topic: Estrogen
Replies: 4
Views: 11459
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