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Anaplasia

Definition

noun

A condition in which a cell or group of cells dedifferentiated, often accompanied with rapid cellular division, as observed in most malignant tumors


Supplement

Anaplasia occurs when a previously differentiated cell or group of cells dedifferentiated -- meaning the cell lost its structural and functional differentiation.

Most cells that dediffentiated tend to divide rapidly, as seen in most malignant tumors. Anaplastic cells are identifiable by their enlarged nucleus or by having several nuclei. They are characteristically larger than their normal counterpart.


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