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Loss of structural differentiation within a cell or group of cells often with increased capacity for multiplication, as in a malignant tumor.Opposite of cell specialisation, cells retire from their specialised form into a more simplistic, unspecialised cell.anaplasia

(Science: pathology, oncology) characteristics of a cell (structure and orientation) that make it identifiable as a cancer cell and malignant.

there is lack of differentiation, which is characteristic of some tumour cells.

Origin: gr. Plassein = to form