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Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropioni

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

(Science: chemical) Alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid. An ibotenic acid homolog and glutamate agonist. The compound is the defining agonist for the ampa subtype of glutamate receptors (receptors, ampa). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Pharmacological action: excitatory amino acid agonists.

chemical name: 4-Isoxazolepropanoic acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo-


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