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Allosteric Enzyme

An enzyme that can be in two states, active and inactive, in the first instance, the process is relatively normal, where the enzyme binds to its binding Site and carries out its reaction. In the second instance, the enzyme is unable to attach itself to the binding Site. This is due to a modulator molecule which alters the shape of the binding Site, making it inactive.allosteric enzyme

(Science: biochemistry, chemistry) a regulatory enzyme whose activity is modified by the noncovalent binding of a particular metabolite at a site (the allosteric site) other than the active site.


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Enzymes

Assuming you mean regulation of rate of one enzyme, then you're interested in things such as posttranslational regulation (phosphorylation). As jonmoulton mentioned, allosteric regulators are important.

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by JackBean
Tue Aug 21, 2012 9:15 pm
 
Forum: Molecular Biology
Topic: Enzymes
Replies: 23
Views: 9442

Re: Enzymes

"Also, in terms of the rate at which an enzyme acts, other than substrate concentration and reaction rate, are there any ... and pH affect rate. Many enzymes are controllable by other enzymes -- look at allosteric regulation: http://en.wikipedia.org/wiki/Allosteric

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by jonmoulton
Mon Aug 20, 2012 10:37 pm
 
Forum: Molecular Biology
Topic: Enzymes
Replies: 23
Views: 9442

Energy, enzymes & metabolism Questions.

... free energy relate to entropy and enthalpy?", "How does an enzyme promote a chemical reaction?", "What is the active site ... competitive and non-competitive enzyme inhibitors?", "How do allosteric enzymes control feedback regulation in metabolic pathways?" ...

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by JackBean
Fri Sep 30, 2011 1:35 pm
 
Forum: Molecular Biology
Topic: Energy, enzymes & metabolism Questions.
Replies: 4
Views: 7683

Energy, enzymes & metabolism Questions.

... between ATP structure and its potential energy? How does an enzyme promote a chemical reaction? What is the active site of an enzyme? ... What is the relationship between enzymes and coenzymes? How do allosteric enzymes control feedback regulation in metabolic pathways? What ...

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by arasfromexile
Fri Sep 30, 2011 10:19 am
 
Forum: Molecular Biology
Topic: Energy, enzymes & metabolism Questions.
Replies: 4
Views: 7683

Re: Special case of enzyme inhibitor?

... The substance I used was a crude extract which I introduced into the enzyme. Is it possible that the reason for the increase in maximum velocity ... to other compounds present in the crude extract that may have become an allosteric effector on the enzyme or competed with the substrate? If so, ...

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by Azure
Thu Feb 17, 2011 11:52 am
 
Forum: General Discussion
Topic: Special case of enzyme inhibitor?
Replies: 3
Views: 2305
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