Dictionary » A » Alkylation

Alkylation

Definition

noun

The process in which the alkyl group is added or substituted from one molecule to another.


Supplement

The alkyl group may be transferred as an alkyl carbonation, a free radical, etc., as in the reaction of alkenes with alkanes to make high-octane fuels.

Alkylation is also used in chemotherapy to kill the cancer cells by damaging DNA.


See also: alkylating agent


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Detoxification

The conjugation can take place with UDP-glucuronate, PAPS to form sulphate, alkylation by S-adenosylmethionine or acylation by acetyl-CoA, conjugation with amino acids (Gly, Gln) or with GSH etc.

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by JackBean
Wed Nov 04, 2009 1:23 pm
 
Forum: General Discussion
Topic: Detoxification
Replies: 5
Views: 3040


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