Dictionary » A » Alkylation




The process in which the alkyl group is added or substituted from one molecule to another.


The alkyl group may be transferred as an alkyl carbonation, a free radical, etc., as in the reaction of alkenes with alkanes to make high-octane fuels.

Alkylation is also used in chemotherapy to kill the cancer cells by damaging DNA.

See also: alkylating agent

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The conjugation can take place with UDP-glucuronate, PAPS to form sulphate, alkylation by S-adenosylmethionine or acylation by acetyl-CoA, conjugation with amino acids (Gly, Gln) or with GSH etc.

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by JackBean
Wed Nov 04, 2009 1:23 pm
Forum: General Discussion
Topic: Detoxification
Replies: 5
Views: 3504

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