noun, plural: agonists
(pharmacology) There are different kinds of agonists:
- Full agonists have an affinity for and activate a receptor.
- Partial agonists bind and activate a receptor but have only partial efficacy at the receptor (compared with full agonists).
- Inverse agonists reverse constitutive activity of receptors.
- Co-agonists work with other co-agonists to produce the desired effect together.
Word origin: From the Greek αγωνιστής (agōnistēs), contestant; champion; rival < αγων (agōn), contest, combat; exertion, struggle < αγω (agō), I lead, lead towards, conduct; drive.
Related forms: agonistic (adjective).
Related phrases: physiological agonist.
See also: agonism.