Dictionary » A » Affinity constant

Affinity constant



(1) A mathematical constant that describes the bonding affinity between two molecules at equilibrium.

(2) The reverse of dissociation constant.


It is the measure of the affinity of an enzyme for its substrate. An example is the measure of the strength of binding in the hapten-antibody interaction.

Symbol: Ka


Compare: dissociation constant

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Competitive receptor-ligand Binding

... dose-response curve will be shifted to the right in the presence of a constant concentration of an antagonist that binds to the same receptor" ... think of is that there could be another binding site (one of lower affinity) which would increase the maximal response, any thoughts?

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by someguy456345
Thu Feb 24, 2011 7:48 pm
Forum: Cell Biology
Topic: Competitive receptor-ligand Binding
Replies: 0
Views: 2159

Homework help!

... of different species. Which animal has hemoglobin with the highest O2 affinity and which has hemoglobin with the lowest O2 affinity? Animal P50 ... oxygen affinity increases, and vice versa. However they are giving me a constant P50 and an O2 capacity value... I can't seem to get what they what ...

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by stupodity
Wed Dec 08, 2010 3:22 am
Forum: General Discussion
Topic: Homework help!
Replies: 2
Views: 2479


... but not sure! 3) Which ONE of the following statements is INCORRECT ? Affinity is: A measure of the strength of the binding of antigen to antibody ... change of the Ag/Ab interaction Always equal to avidity The association constant of the Ag/Ab equilibrium 4) Select the ONE answer that is CORRECT. ...

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by pinkypig
Thu Feb 05, 2009 5:12 pm
Forum: General Discussion
Replies: 0
Views: 3486

Insulin hormone

... cell membrane in the small intestine) GLUT3: low Km and thus very high affinity for glucose --> expressed in the brain, because it's saturated and thus keeps glucose transport into the brains constant till glucoseconcentration to 2 mM --> the mechanism of how insulin ...

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by sdekivit
Wed Jan 24, 2007 4:43 pm
Forum: Physiology
Topic: Insulin hormone
Replies: 13
Views: 13408

Subspecies comparison of the Genus: Corucia

... appears to exist between Bougainville and Choiseul. "There is an affinity along the lines of Bougainville - Choiseul, separated by the Bougainville ... (underlined), the ecological niche in this subspecies remained constant. This is based on a pattern in the Scincidae where the more arboreal ...

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by Brian - LCRC
Sat Aug 26, 2006 1:15 pm
Forum: Evolution
Topic: Subspecies comparison of the Genus: Corucia
Replies: 1
Views: 10934
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