Dictionary » A » Affinities



1. An inherent likeness or relationship.

2. A special attraction for a specific element, organ or structure.

3. (Science: chemistry) The force that binds atoms in molecules, the tendency of substances to combine by chemical reaction.

4. The strength of noncovalent chemical binding between two substances as measured by the dissociation constant of the complex.

5. (Science: immunology) a thermodynamic expression of the strength of interaction between a single antigen binding Site and a single antigenic determinant (and thus of the stereochemical compatibility between them), most accurately applied to interactions among simple, uniform antigenic determinants such as haptens. Expressed as the association constant (k litres mole 1), which, owing to the heterogeneity of affinities in a population of antibody molecules of a given specificity, actually represents an average value (mean intrinsic association constant).

6. (Science: chemistry) The reciprocal of the dissociation constant.

Origin: L. Affinitas = relationship

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Re: Are carbohydrates hydrophobic?

... elements, always along with the oxygen, tend to be polar in their bonds: "You should remember that oxygen and nitrogen have relatively high affinities for electrons, and therefore oxygen-carbon and oxygen- hydrogen bonds as well as nitrogen-hydrogen bonds are all polar bonds (with the oxygen ...

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by HectorEnriquezC
Fri Aug 30, 2013 1:36 am
Forum: Molecular Biology
Topic: Are carbohydrates hydrophobic?
Replies: 7
Views: 20815

Re: Cytokine - Receptor concepts

... for example induces naive T cells to become Th0 cells, and then only after that to they become Th1 or 2 cells depending on what they encounter Affinities are usually defined by the structure of the receptor, and with T cells the arrangement of alpha and beta chains whilst they mature in the ...

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by Nataly56
Thu Jul 14, 2011 7:47 am
Forum: Cell Biology
Topic: Cytokine - Receptor concepts
Replies: 7
Views: 16994

How does negative selection in the thymus get around viral a

... receptor signals. Although the article focused mainly on autoimmunity, they said that many clonal TCRs can recognize several epitopes with varying affinities - with varying outcomes. So even if a virus could invade the thymus and thus eliminate the T cells specific for it, the somewhat loose nature ...

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by biohazard
Tue Jun 28, 2011 6:52 am
Forum: Human Biology
Topic: How does negative selection in the thymus get around viral a
Replies: 3
Views: 7101

Cellular Respiration

... time, so they cannot just fermentate pyruvate to lactate. 3b) I think this is not very well known yet. But probably by changes in structure, the affinities of particular amino acid residues change and thus the protons are transported 3c) it does not create ATP. It only closes ADP and phosphate ...

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by JackBean
Fri Dec 31, 2010 10:53 am
Forum: Cell Biology
Topic: Cellular Respiration
Replies: 2
Views: 2489


... of transcription, what guides the movement of RNA out of the nucleus in eukaryotic cells, or the movement of any molecules? Is it because of their affinities for other molecules? And where do affinities come from? Thanks.

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by dkav
Thu Dec 30, 2010 9:57 pm
Forum: Molecular Biology
Topic: Transcription
Replies: 4
Views: 2502
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