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Adenosine

Definition

noun

A purine nucleoside that has adenine bound to a ribose sugar by a glycosidic bond.


Supplement

Adenosine is found in all living organisms as a structural component of important biomolecules such as DNA and RNA. It is also a major molecular component of ATP, ADP, and AMP. It is thus involved in various physiologic processes such as energy transfer (e.g. as ATP) and signal transduction (i.e. as cAMP). It also acts as an inhibitory neurotransmitter, presumably in promoting sleep.

Its pharmacologic action includes vasodilation, anti-arrhythmia, and analgesia. When given intravenously, adenosine can cause transient heart block in the AV node.


Word origin: combination of adenine + ribose.

IUPAC name: (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Molecular formula: C10H13N5O4

Synonym: Adenine riboside, beta-D-Adenosine.

Compare: deoxyadenosine.
See also: nucleoside.

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Re: How did endosymbionts coordinate replication?

... of mitochondria, this paper discusses an influence of tumor necrosis factor alpha on mitochondrial replication while exploring the effect of adenosine on that regulatory system. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0098459 Kalogeris TJ, Baines C, Korthuis RJ ...

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by jonmoulton
Wed Jun 11, 2014 2:08 pm
 
Forum: Cell Biology
Topic: How did endosymbionts coordinate replication?
Replies: 9
Views: 4102

Sequencing Primers

... mapping. However, the bases do not need to be known. Dimethylsulfate is used to determine purines (G and A). Guanosine is affected more than Adenosine and gel bands appear darker on a gel. Hydrazine works for pyrimidines (C and T). Only Cystine bases are cleaved in high salt and are distinguished ...

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by DougB
Mon Apr 23, 2012 6:25 pm
 
Forum: Genetics
Topic: Sequencing Primers
Replies: 4
Views: 3102

Maximum Life Span of Animals, Fishes and Birds.

... into the cells. Aerobic respiration, as opposed to anaerobic, uses oxygen as well as a monosaccharide (glucose, galactose, fructose etc) to create adenosine triphosphate (ATP). This does, however, cause the release of free radicals, which can damage the cell nucleus and cause cellular ageing. This ...

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by Squirrell
Wed Feb 15, 2012 2:07 am
 
Forum: Zoology Discussion
Topic: Maximum Life Span of Animals, Fishes and Birds.
Replies: 9
Views: 7874

I want you like X wants Y type sentences

Or I want to couple with you like Pyruvate Kinase wants to couple with Adenosine Triphosphate hydrolysis.

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by billyfisher100
Mon Jan 23, 2012 6:46 pm
 
Forum: General Discussion
Topic: I want you like X wants Y type sentences
Replies: 10
Views: 6592

Re: ATP ase vs. ADP ase

ATPases are a class of enzymes that catalyze the decomposition of adenosine triphosphate (ATP) into adenosine diphosphate (ADP) and a free phosphate ion. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive ...

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by bellyjelly
Tue Jul 12, 2011 7:20 am
 
Forum: Molecular Biology
Topic: ATP ase vs. ADP ase
Replies: 9
Views: 10892
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