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Addition mutation

Definition

noun

A type of gene mutation wherein the addition (as well as deletion) of (a number of) nucleotide(s) causes a shift in the reading frame of the codons in the mRNA, thus, may eventually lead to the alteration in the amino acid sequence at protein translation.


Supplement

Mutations involving the genes are of two major types:


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Things that cause cancer (in modern humans who live longer)

Unless I am mistaken, the higher rate of mutations in older parents is not linked to eating red meat. What comes to the increased ... high-energy, high-protein fat and meat from animals was probably a welcome addition to the neolithic diet, making mothers (and babies alike) more healthy and ...

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by biohazard
Wed Oct 31, 2012 11:05 am
 
Forum: Evolution
Topic: Things that cause cancer (in modern humans who live longer)
Replies: 4
Views: 4009

mutations annotations and analysis

Hi, I'm performing a computational analysis on mutations and currently trying to build a data set of specific mutation that I ... these mutations? (for example, looking only on the longest transcript). In addition, assuming I have only a single transcript, which tables do you suggest ...

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by nonish
Sun Sep 16, 2012 8:06 am
 
Forum: Bioinformatics
Topic: mutations annotations and analysis
Replies: 0
Views: 1665

Molecular gene (genome) concept scientifically untenable

... Johannsen introduced the notions of “genotype” and “phenotype”. In addition, he proposed the term “gene” for the elements of the genotype. Johannsen ... the synthesis of another structure like itself, [in] which even the mutations of the original gene are copied. [We] do not know of such things ...

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by PAWahid
Wed May 02, 2012 4:54 am
 
Forum: Molecular Biology
Topic: Molecular gene (genome) concept scientifically untenable
Replies: 12
Views: 28991

Theories - Origin of Life

Another thing to please keep in mind, these examples of random mutations provide evidence of what is termed micro evolution and in a negative ... and every new mutation would have the potential to build on it. Also in addition to this one that I have cited, I am informed that there are some 200 ...

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by AstraSequi
Tue Mar 27, 2012 2:32 am
 
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 562
Views: 929119

Theories - Origin of Life

There are random mutations that rearrange the DNA of the cell. These mutations are invariably the result ... and cause them to have a higher error rate in DNA synthesis. (Probably by addition of certain mutagens, or knockout/inhibition of a repair enzyme.) If the result ...

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by AstraSequi
Tue Mar 27, 2012 2:25 am
 
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 562
Views: 929119
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