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(Science: cell biology, protein) A family of integral plasma membrane proteins which, when overexpressed, function as adenosine triphosphate-dependent efflux pumps, causing multidrug resistance.

Mammalian p-glycoproteins are encoded by small mdr gene families. There are several isotypes in multiple species.

See: multidrug transporter.

Retrieved from "http://www.biology-online.org/bodict/index.php?title=P-glycoprotein&oldid=41990"
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