Nonsense mutation

Revision as of 08:55, 2 March 2009 by Honee_v (Talk | contribs) (updated page)



A form of point mutation resulting in a nonsense codon that does not code for an amino acid and leads to a protein product that is early truncated.


In nonsense mutations, the protein product from a sequence of DNA with a nonsense mutation is prematurely truncated, incomplete and often nonfunctional. Genetic disease such as Duchenne muscular dystrophy is caused by a nonsense mutation in gene responsible for a specific protein, for example, dystrophin.

Compare: missense mutation, silent mutation.
See also: point mutation

Retrieved from ""
First | Previous (Nonsense codon) | Next (Nonsense strand) | Last
Please contribute to this project, if you have more information about this term feel free to edit this page.