Mastocytosis

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Mastocytosis

(Science: radiology) proliferation of mast cells, seen in haematopoietic regions of skeleton, sclerotic bone lesions, diffuse, patchy sclerosis, discrete, irregular, sclerotic nodules, rarely lytic lesions with densely sclerotic margins, mast cells elaborate histamine producing flushing, tachycardia, nausea, diarrhoea, pigmented, pruritic rash (urticaria pigmentosa), hepatosplenomegaly, adenopathy, thrombocytopenia; increased or decreased wbcs

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