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A technique that removes toxic substances from the blood by adsorption process, that is by allowing the passage of blood through columns of adsorptive substance, such as activated charcoal or carbon, and resins. The treatment is said to be 'extracorporeal' because the blood is pumped outside the patients body.

It is an effective treatment for removing some poisons from the blood, particularly those that bind to proteins in the body or are difficult to dissolve in water. Hence, it is used to treat overdoses of barbiturates, meprobamate, glutethimide, theophylline, digitalis, carbamazepine, methotrexate, ethchlorvynol, and acetaminophen.

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