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Any of the flavin-bound enzymes in mitochondria that catalyze the reduction of cytochrome and similar compounds


One use of diaphorase is diaphorase staining, which is used to mark active mitochondria wherein it uses NADH (or NADPH) as substrate to reduce dyes.

Diaphorase is also described to be associated with methemoglobinemia, a condition caused by a deficiency of diaphorase, particularly NADH methemoglobin reductase.

Word origin: Greek diáphor (different, unlike)

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