R-factors- antibiotic resistance?

[allabout]

Antibiotic resistance is caused both by mutation within bacterial cells and transfer of antibiotic resistance plasmids (R-factors) from one bacterium to another bacterium.

Why does the latter cause the biggest problem in regard to proliferation of antibiotic resistance?

Answer please

[canalon]

Well just think in term of spread of the resistance if it is on a plasmid or inside a chromosome. What difference the location would make?

[Fruitfly]

And another reason,in my opinion, probability of conjugation is higher than probability of antibiotic resistance mutation