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Are tissues in the body capable of sensing pain?

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Are tissues in the body capable of sensing pain?

Postby deostroll » Tue Dec 25, 2007 7:40 pm

I am very curious to know
A) what is a tissue?
B) do tissues usually have nerve cells in them? If they do not, how does a tissue detect damage?
C) when a tissue is damaged do we necessarily feel pain?
D) if at all there are pain receptors, how can we evolutionarily explain how they got there in the first place?
PS: I happen to be a philosopher, rather than a true scientist...
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Re: Are tissues in the body capable of sensing pain?

Postby Revenged » Wed Dec 26, 2007 11:33 pm

deostroll wrote:I am very curious to know
A) what is a tissue?
B) do tissues usually have nerve cells in them? If they do not, how does a tissue detect damage?
C) when a tissue is damaged do we necessarily feel pain?
D) if at all there are pain receptors, how can we evolutionarily explain how they got there in the first place?


A) tissue is a group of cells that have a similar function

B) tissue damage causes an acute inflammation... it is the inflammation that causes activation of sensory nerves in the tissue... once these nerves are activated they activate a specific area of the brain (primary sensory cortex)...

C) no, not necessarily... it depends how much damage there is... but pain sensation is both a physiological and psychological responce... many people have very traumatic sports injuries and they don't feel the pain to much after the event... as adrenaline may well delay a pain responce... but we also have other endogenous pain killers in bodies (endogenous opioids, neurotransmitters...etc.)

D) pain responce is an evolutionary advantage... how can you survive without responce to pain?... there are people do exist with no pain responces as they have mutations of subtypes of sodium channels... however, children with these conditions tend to cut off their fingers and break limbs without noticing...!
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Re: Are tissues in the body capable of sensing pain?

Postby deostroll » Thu Dec 27, 2007 5:42 am

Revenged wrote:A) tissue is a group of cells that have a similar function


Do tissues move around then? Can they be looked upon as a colony? Is there any particular advantage when cells come together like this and form a tissue? Can they be isolated or separated?

Revenged wrote:B) tissue damage causes an acute inflammation... it is the inflammation that causes activation of sensory nerves in the tissue... once these nerves are activated they activate a specific area of the brain (primary sensory cortex)...

Acute inflammation...? I get the picture that the cell walls collapse and release bio-chemicals, which causes some inequilibrium, which inturn causes the nerve cells to fire crazy...I hope this is what you meant. (Then I wonder how come these neural receptors happen to be quite near these tissues if they are not in the group as such)?
PS: I happen to be a philosopher, rather than a true scientist...
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Re: Are tissues in the body capable of sensing pain?

Postby volcob » Thu Dec 27, 2007 8:47 am

deostroll wrote:
Revenged wrote:A) tissue is a group of cells that have a similar function


Do tissues move around then? Can they be looked upon as a colony? Is there any particular advantage when cells come together like this and form a tissue? Can they be isolated or separated?

Revenged wrote:B) tissue damage causes an acute inflammation... it is the inflammation that causes activation of sensory nerves in the tissue... once these nerves are activated they activate a specific area of the brain (primary sensory cortex)...

Acute inflammation...? I get the picture that the cell walls collapse and release bio-chemicals, which causes some inequilibrium, which inturn causes the nerve cells to fire crazy...I hope this is what you meant. (Then I wonder how come these neural receptors happen to be quite near these tissues if they are not in the group as such)?



A) tissues are group of similar cells doing similar functions they can look like a colony but they are not, in the sense that colonies do not always depend on each other to function
while tissues get affected if one or two of its neighboring cells get rogue or gets killed

Tissues usually don't roam around in errand but some of the connective tissues are exempted (eg.blood)

you said that you are more of a philosopher so ill give this answer the advantage of having this tissue is the same as the grouping of humans(imagine yourself alone or far away from another)

B) we are not tissues so we cannot concretely know :? but of course they have it! you might ask how about in cells?

in cells they do also have the nerve cells but in the molecular level they have protein sensors and the affected cells can also trigger the message in other cells via protein messenger regarding the damage the neigboring cells react causing it to respond in tissue level.
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Re: Are tissues in the body capable of sensing pain?

Postby volcob » Thu Dec 27, 2007 8:51 am

volcob wrote:
deostroll wrote:
Revenged wrote:A) tissue is a group of cells that have a similar function


(Then I wonder how come these neural receptors happen to be quite near these tissues if they are not in the group as such)?



thats the principle of the organ system

a system is actually consisting of many different organs interrelating to each other but they do not need to be of the same cell or the same function they just complement the other
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Re: Are tissues in the body capable of sensing pain?

Postby deostroll » Thu Dec 27, 2007 6:17 pm

volcob wrote:the advantage of having this tissue is the same as the grouping of humans(imagine yourself alone or far away from another)
How do cells normally decide or know if this 'act of coming together' actually benefits them?
PS: I happen to be a philosopher, rather than a true scientist...
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Re: Are tissues in the body capable of sensing pain?

Postby Revenged » Fri Dec 28, 2007 12:18 am

deostroll wrote:Acute inflammation...? I get the picture that the cell walls collapse and release bio-chemicals, which causes some inequilibrium, which inturn causes the nerve cells to fire crazy...I hope this is what you meant. (Then I wonder how come these neural receptors happen to be quite near these tissues if they are not in the group as such)?


receptors in the skin respond to damage/inflammation to activate sensory neurones...
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Re: Are tissues in the body capable of sensing pain?

Postby deostroll » Fri Dec 28, 2007 2:33 am

If the spacial arrangement of a neuron is disturbed will the neuron be under some sort of stress so as to activate itself and surrounding neurons? If so, can these "inflammations" cause such level of disturbance?
PS: I happen to be a philosopher, rather than a true scientist...
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Re: Are tissues in the body capable of sensing pain?

Postby deostroll » Fri Dec 28, 2007 2:37 am

volcob wrote:you said that you are more of a philosopher so ill give this answer the advantage of having this tissue is the same as the grouping of humans(imagine yourself alone or far away from another)
I don't have a laboratory. I don't do field explorations, Heck I don't even have a microscope! :) And I am no biologist by profession. I only have the internet for any source of knowledge :!:
PS: I happen to be a philosopher, rather than a true scientist...
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Re: Are tissues in the body capable of sensing pain?

Postby volcob » Sat Dec 29, 2007 9:00 am

volcob wrote:the advantage of having this tissue is the same as the grouping of humans(imagine yourself alone or far away from another)
How do cells normally decide or know if this 'act of coming together' actually benefits them?[/quote]
then we ask the DNAs/RNAs
evolution is probably the answer :lol:
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Re: Are tissues in the body capable of sensing pain?

Postby deostroll » Sat Dec 29, 2007 7:03 pm

volcob wrote:
volcob wrote:evolution is probably the answer :lol:

I want to learn more about this. Where can I find the answers?
PS: I happen to be a philosopher, rather than a true scientist...
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Try here.

Postby GegnianMD » Sat Dec 29, 2007 7:45 pm

science.nhmccd.edu/biol/tissue.html
A. LUCIANO D. GRECO
Biomedicine and peace have to be like two wings of a single condor.
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