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Can XY give birth?

Genetics as it applies to evolution, molecular biology, and medical aspects.

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Can XY give birth?

Postby PoOr » Thu Aug 02, 2007 4:01 pm

I'hv got this question that has puzzled me for a while
My professor gave us a question he wants to see if anyone can answer it.
He asked,

Is it possible for a person that has an XY genotype to physically have a child?

I'm thinking perhaps a hermaphrodite where it's a female phenotype but has Y genotype and maybe little phenotype expression.
I'm thinking of a human with female sexual organs but has a silent Y.

I'hv been searching google but nothing concrete in explaining it.

anyone can shed some light on this?
thanks
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Postby mith » Thu Aug 02, 2007 5:40 pm

Can this person make an egg?
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Postby Darby » Thu Aug 02, 2007 9:39 pm

An abdominal mosaicism or chimera could both set up a functional female system in an XY.
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Postby sdekivit » Fri Aug 03, 2007 7:55 am

must it be human :P
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Postby MrMistery » Fri Aug 03, 2007 10:40 am

sure it can. There have been cases. If the person has a mutation in the SRY gene, he(she) will phenotypically be a female and have a uterus. Select fertile eggs, do in vitro fertilisation, implant then and voila, there's your baby
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Postby PoOr » Fri Aug 03, 2007 11:18 am

Wow your fantastic
I did a search for the SRY gene and i beleive that is the key to an XY genotype able to have a child.

from wikipedia: Individuals with XY genotype and functional SRY gene can have a female phenotype, where the underlying cause is androgen insensitivity syndrome (AIS).

So if there is a mutation in the SRY gene, a female phenotype can get artificially pregnant and give birth.

You guys rock. love this site.
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XY fertile

Postby sllawb » Sat Aug 04, 2007 2:26 am

Also individuals that have a male phenotype but a female genotype(x,x) have the sry gene on one or can even have it on both X chromosomes. They can get the by a transposable element or some other translocating mechanism. Females that have the genotype XXY or XY also have the sry gene but it is a mutant and therefore these females cannot be fertile I dont think. Females with the XY genotype are said to have androgen insensitiviy syndrome. I think it is just a mutation in the gene that encodes the androgen receptor.
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Postby sllawb » Sat Aug 04, 2007 2:27 am

well I just wrote all that and didnt see that there was a post about AIS. Sorry thought i was helping. hahaha
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Postby Revenged » Fri Aug 10, 2007 3:48 pm

MrMistery wrote:he(she)


i think the politically correct term is the "shemale" :lol:
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Postby kotoreru » Fri Aug 10, 2007 5:43 pm

I quite like 'heshe' (hee-shee). Whether it's PC or not is irrelevant lol
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Postby david23 » Wed Aug 22, 2007 3:56 pm

You probably need some sort of invitro fertilization and a surrogate mom. An XY woman might have developmental problems.
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Postby ramya » Mon Sep 24, 2007 6:08 am

MrMistery wrote:sure it can. There have been cases. If the person has a mutation in the SRY gene, he(she) will phenotypically be a female and have a uterus. Select fertile eggs, do in vitro fertilisation, implant then and voila, there's your baby

ya there are cases of such condition.i have read it before in some papers and the major cause probably would be mutation in SRY gene that made the person to lack maleness and retain femaleness. so she might be phenotypically female but genotypically male{XY}.
thanq :D
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