RBC

by **fluktuacia** » Wed May 09, 2007 5:28 am

Are mature RBC capable of protein production when they do not have nucleus? How are they able to transcribe RNA for protein production (they need new proteins.. to repair etc. right?).
And similarly when primary oocyte stops its division at diplotene stage is it capable of transcribtion? if not, how it creates RNA and proteins?

by **david23** » Wed May 09, 2007 9:23 am

mature RBC do not have nucleus, so they cant transcribe or translate. All the proteins they need are made before they become mature.

by **fluktuacia** » Thu May 10, 2007 9:11 am

and the proteins they have made before maturation is sufficient to supply their function? aren't there different sources of proteins or other ways of their production?
and what about that primary oocyte?

by **Darby** » Thu May 10, 2007 3:16 pm

An RBC is pretty much just a bag of hemoglobin anyway - not a lot of metabolic processes there.

Not sure about the oocyte, but I know enough to know NOT to apply "rules" of what can and can't happen at certain times to real-world biological systems. Biology is a system of exceptions.

by **david23** » Fri May 11, 2007 3:51 pm

RBC make everything they need before fully functioning, and then get rid of their nucleus.

About primary oocyte, are you perhaps thinking that since the chromosomes are so tightly wound, that they cant be used to produce proteins? There are regulatory proteins that allow transcription to happen. Am I knocking up the right tree here?

by **Revenged** » Fri May 11, 2007 11:23 pm

I can't think of a reason why a primary oocyte won't be able to undergo transciption...

by **david23** » Sat May 12, 2007 7:07 pm

fluk u need to give some feedbacks so i can know how to answer u

by **fluktuacia** » Mon May 14, 2007 6:50 am

sorry i wasn't here at the weekend:).. well, i agree with those RBC (i have the same explanation, i was just doubtful whether RBC can survive just with the proteins made before the maturation)
what i meant in the case of the oocyte was, that during division the transcribtion is halted and since the primary oocyte stops at the middle of it (diplotene stage) proteine production shoud be stopped as well.. so the same problem as in RBC - how it can survive for years withouth protein production

by **kotoreru** » Mon May 14, 2007 8:01 am

Erythrocytes do not survive for years. I actually think the average life expectance is 3 weeks?

by **Dustfinger** » Mon May 14, 2007 11:07 am

kotoreru wrote:I actually think the average life expectance is 3 weeks?

Not 120 days ???

by **david23** » Mon May 14, 2007 7:24 pm

everything made to survive those 120 days is made beforehand.

by **Poison** » Mon May 14, 2007 8:00 pm

Dustfinger wrote:
kotoreru wrote:I actually think the average life expectance is 3 weeks?

Not 120 days ???

yes 120 days.

RBC

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