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can a woman produce sperm?

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can a woman produce sperm?

Postby cracked_doc » Wed Apr 18, 2007 9:38 am

A friend of mine told me that there have been such a news...have you ever heard of a thing like this? and is it possible?
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Postby Dr.Stein » Wed Apr 18, 2007 10:27 am

In normal condition: N O
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Re: can a woman produce sperm?

Postby zami'87. » Wed Apr 18, 2007 3:13 pm

cracked_doc wrote:A friend of mine told me that there have been such a news...have you ever heard of a thing like this? and is it possible?

If u mean on experiments with 2 eggs It wouldn't be possible to get viable embryo because DNA metilation would be different from the one of sperm cell...as I remember. It's not possible... but yeah I heard they are experimenting with stem cells

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Postby Darby » Wed Apr 18, 2007 4:46 pm

Shouldn't work - there are at least a couple of Y chromosome genes that would be needed, and if you have a Y you are by definition male.

They may have seen the recent news of the use of sperm stem cells to produce a few other type of body cells and gotten things confused...
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Postby kotoreru » Thu Apr 19, 2007 11:01 am

Well the question was actually if sperm cells could be made, not male gametes. The Y-chromosome has no bearing on this, otherwise clearly males would produce eggs as well as sperm depending on which sex chromosome made it into the nucleus.

Under normal conditions, clearly no women cannot make sperm *shudders*. But I suppose theoretically if one were to take an immature egg cell and expose it to certain chemical cues and then nurture it...a sperm cell could be made.

Yes, much like the sperm-from-stem cell experiment that Darby speaks of.
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Postby Darby » Thu Apr 19, 2007 4:25 pm

The point I was making was that spermatogenesis requires at least a couple of genes carried on the Y chromosome. Which way the sex chromosomes go at that point isn't an issue (and sperm cells are the same thing as male gametes, at least whenever I've heard them discussed).

Males can make egg cells, when you get hermaphroditic mosaicism (embryonic abdominal cells divide improperly, producing a cell line without a Y chromosome).

And the experiments I referred to weren't making sperm, they were using sperm stem cells (spermatogonia, I assume, but I don't remember it being specified) to produce other kinds of cells.
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Postby kotoreru » Thu Apr 19, 2007 10:26 pm

Fair enough, but I think complicating the issue with hermophroditic matters is not neccessary.

And sperm cells are not the same as male gametes. Consider dioecious plants...
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Postby Dr.Stein » Fri Apr 20, 2007 4:20 am

Spermatozoon is not male gamet? So what is that? :?

The reproductive system between plants and animals is different, so I think we cannot discuss it together here. According to the topic, it is animal reproductive system so, well... :)
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Postby arian » Fri Apr 20, 2007 7:07 am

the sex is determines from SRY region which is a gene that is situated on the short branch of Y chromosome. this determine that the embryo will be male. Thus being female the paternal chromosome is X and maternal is X too so XX gives female embryo. On both cases they produce a chain reactions which activate different hormones female or male hormones. The Male hormone is testosterone and female is progesterone. Those hormones have the secondary effects on individual body and this is related also with sexual hormones and organs. So a woman can not produce sperm becasue she needs to have testicules and the sperm is produced on special cells of testicules and they need to be activated by testosterone (male hormon).
So in a few words there is no any chance that a woman CAN NOT produce sperm.
there are known different syndromes like Turnes Syndrome when they have XXY, or Chlainepher Syndrome XXXY, and so on. But they are sterile.
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Postby Darby » Fri Apr 20, 2007 3:35 pm

I think I see what you're saying - in your definition, a sperm carrying a Y chromosome is a male gamete. The thing is, that's a fairly odd definition.

As mentioned above, most of us are used to the terminology of sperm being the most common form of gamete produced by males (and that applies to plants, too, dioecious or monoecious), or male gametes, with egg cells / ova being female gametes. The gametes define the genders, after all.

And, by your definition, many organisms would have no male gametes, since determinism by chromosome is the minority approach to gender.
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Postby Darby » Sun Apr 22, 2007 4:29 pm

I just saw an article on the study that precipitated this - there was a group that generated sort-of spermatogonia from bone stem cells. They did use male donors, though.

I guess that might make it possible to treat men rendered sterile by cancer treatments.

Or get mice to produce human sperm...
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Postby scorpio88 » Wed Apr 25, 2007 6:03 am

No way in normal Conditions...............
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