Genetics as it applies to evolution, molecular biology, and medical aspects.
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in bio class we have a new subject. i am having difficulty separating the difference between the following:
x linked dominant
x linked recessive
My exams are next tuesday so any help explaining what the differences are and how to recognize them would be greatly appreciated.
Last edited by student1000 on Thu Jun 02, 2005 9:39 pm, edited 1 time in total.
A pattern of Mendelian inheritance whereby an affected individual possesses one copy of a mutant allele and one normal allele. (In contrast, recessive diseases require that the individual have two copies of the mutant allele.) Individuals with autosomal dominant diseases have a 50-50 chance of passing the mutant allele and hence the disorder onto their children. Examples of autosomal dominant diseases include Huntington's disease, neurofibromatosis, and polycystic kidney disease.
Describes a trait or disorder requiring the presence of two copies of a gene mutation at a particular locus in order to express observable phenotype; specifically refers to genes on one of the 22 pairs of autosomes (non-sex chromosomes)
Describes a dominant trait or disorder caused by a mutation in a gene on the X chromosome. The phenotype is expressed in heterozygous females as well as in hemizygous males (having only one X chromosome); affected males tend to have a more severe phenotype than affected females.
A mode of inheritance in which a mutation in a gene on the X chromosome causes the phenotype to be expressed in males who are hemizygous for the gene mutation (i.e., they have only one X chromosome) and in females who are homozygous for the gene mutation (i.e., they have a copy of the gene mutation on each of their two X chromosomes). Carrier females who have only one copy of the mutation do not usually express the phenotype, although differences in X-chromosome inactivation can lead to varying degrees of clinical expression in carrier females
A gene on the Y chromosome. A Y-linked gene is by necessity passed from father to son, since the Y chromosome can only be transmitted by a man to his male progeny.
It has often been said that little is known about whether specific genes are or are not Y-linked. This is no longer true. As of the year 2000, a number of genes were known to be Y-linked including:
* ASMTY (which stands for acetylserotonin methyltransferase),
* TSPY (testis-specific protein),
* IL3RAY (interleukin-3 receptor),
* SRY (sex-determining region),
* TDF (testis determining factor),
* ZFY (zinc finger protein), PRKY (protein kinase, Y-linked),
* AMGL (amelogenin),
* CSF2RY (granulocyte-macrophage colony-stimulating factor receptor, alpha subunit on the Y chromosome),
* ANT3Y (adenine nucleotide translocator-3 on the Y),
* AZF2 (azoospermia factor 2),
* BPY2 (basic protein on the Y chromosome),
* AZF1 (azoospermia factor 1),
* DAZ (deleted in azoospermia),
* RBM1 (RNA binding motif protein, Y chromosome, family 1, member A1),
* RBM2 (RNA binding motif protein 2) and
* UTY (ubiquitously transcribed TPR gene on Y chromosome).
"Take four red capsules, in ten minutes take two more. Help is on the way."
----- Voice from the Medicine Cabinet
Don't tell me you knew all those genes by heart because i'll start crying. They don't even ask that kind of thing at IBO
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
Knowing and explaining are different. Explaining (or you can call teaching) something to someone needs more knowledge and proffesionality.
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I know what you mean. I know more bio than some teachers in my school(No, i'm not bragging, they are just stupid ) and yet they can explain them better than me...
Actually we call them that because they went to university and couldn't get a better job after that
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