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Postby KTK » Thu Apr 28, 2005 9:42 pm

any one know any good websites i can use for this topic?
Last edited by KTK on Thu May 12, 2005 11:06 am, edited 2 times in total.
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Postby Chris4 » Fri Apr 29, 2005 10:54 am

Acitve MPF is a kinase that phosphorylates Lamin proteins of the nuclear lamina, and promotes nuclear envelope breakdown. It also promotes mitotic spindle formation and chromosome condensation.
Is that all you need for the first question?
Im not sure about the other questions. This is not one of my favourite areas of the cell cycle. I wish they'ed just call it Cyclin B/Cdk1. You know MPF isnt even mentioned in the massive textbook Molecular Biology of the Cell (4th Edition) by Alberts et al. Highly recommended textbook, standard for degree level.
I think you should refer to it as CyclinB/Cdk1, as MPF is mainly used for Xenopus. MPF is just active CyclinB/Cdk1. Oh and Cdc2 is a synonym of cdk1, which I have been told should really only be used for yeast.
Eukaryotic cell cycle - Active CyclinB/Cdk1
Xenopus - MPF
Yeast - CyclinB/Cdc2
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