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The A in DNA

Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures in the field.

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The A in DNA

Postby vertex87 » Thu Jan 13, 2005 3:01 pm

Why is DNA an acid? (as its name suggests..) :oops: What gives the DNA the acidic property?
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Postby Poison » Thu Jan 13, 2005 5:33 pm

Yes, DNA is an acid. In the structure of DNA, there is sugar (deoxyribose), a phosphate ion, and a nitrogenous base.
the phosphate ion gives the acidic property. :)
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Postby biostudent84 » Fri Jan 14, 2005 5:07 pm

Which is kind of funny because the nitrogen base really IS a base. One acid made up of a long chain of bases.
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Postby Freedom » Fri Jan 14, 2005 8:25 pm

Isn't DNA amazing. :D
"Always remember that you are unique. . . just like everybody else."
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DNA as an acid

Postby 2810712 » Sat Jan 22, 2005 5:48 am

Ok. DNA consists of both acidic subunits and basic subunits ; also their no. is nearly equal; then why is DNA acidic. I think, the strength of acid [po3]is more than base [N-bases]. but, how will U compare the strength of an acid with that of a base ?
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Re: DNA as an acid

Postby dandan » Wed Apr 13, 2005 7:31 am

2810712 wrote:Ok. DNA consists of both acidic subunits and basic subunits ; also their no. is nearly equal; then why is DNA acidic. I think, the strength of acid [po3]is more than base [N-bases]. but, how will U compare the strength of an acid with that of a base ?
hsg


well, you can compare the strength of the acid by comparing it to the base strength through Kb and Ka values, where Ka = Kw/Kb.

also, since the phosphate backbone is on the outside, and the bases are hidden safely inside due to the structure of the DNA, only the acidic portion is free to react with the outside environment... thus making it more important.
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the A in DNA

Postby dr.pnj » Sat Apr 16, 2005 11:39 am

:lol:
what a coincidence
my teacher asked us the same q in our class quiz today
the ans is
the phosphoric acid present in the DNA gives it its acidic nature
h3po4 itself becomes po3(-3)
one oxy is negatively charged and another one contains a lone pair of e-
the other two are bonded
one to upper 3rd c of deoxyribose sugar and second to 5 c of lower sugar
so two oxy atoms are freefor rxn
while in dna the bases are paire d by hydrogen bonds which may be broken but req energy fot that so the acidic nature
hope you get that :idea:
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