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What is the source of new nucleotides for replication?

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What is the source of new nucleotides for replication?

Postby Havoc » Mon Apr 11, 2005 12:02 am

Where does the new nucleotides come from in a DNA replication?
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Re: What is the source of new nucleotides for replication?

Postby Arty » Mon Apr 11, 2005 12:23 pm

Havoc wrote:Where does the new nucleotides come from in a DNA replication?

This process occurrs in the nucleus because it has free(I don't know if this may be the right term) nucleotides
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De novo synthesis

Postby cytochromeP » Fri Apr 15, 2005 12:25 pm

Nucleotide = ribose sugar + phosphate + nitrogen base

Of these phospate is readily available in the cytopasm. (i guess)
ribose is made by utilising the HMP shunt pathway of glucose breakdown
nitrogen bases (purines n pyrimidines) have there own de novo synthetic pathways from simpler components.
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Postby MrMistery » Wed Apr 27, 2005 8:27 pm

You can take ribose and dezoxiribose from food you know...
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Postby Jelanen » Mon May 02, 2005 10:53 pm

Actually, nucleotides are used in DNA replication/repair/etc. in a triphosphate form(eg. ATP, CTP, GTP, TTP). These are also used in other cellular processes in addition to DNA uses. Just off the top of my (shaved) head, ATP and GTP are both used to store energy for other processes.
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Postby MrMistery » Tue May 03, 2005 6:42 pm

I have also heard of a UTP... it is also used to store energy but that is all i know
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Postby thank.darwin » Tue May 03, 2005 9:31 pm

MrMistery wrote:I have also heard of a UTP... it is also used to store energy but that is all i know


Could you find more information about that... Thank-you
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Postby MrMistery » Wed May 04, 2005 6:14 pm

No i can't. When i went to the national olimpic lot i had classes at the biology university and my cellular biology professor told me that but he didn't say anything else. Anyway, it is not important
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Postby Poison » Wed May 04, 2005 6:49 pm

I don't know much about it but UTP (Uridine triphosphate) is like ATP. It is used as the energy source in polisaccharide synthesis.
I will try to find more but I have no further info for now.
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Postby thank.darwin » Wed May 04, 2005 9:10 pm

Thank-you Poison and MrMistery
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Postby Jelanen » Wed May 04, 2005 9:16 pm

Poison is on the money with that.
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Postby MrMistery » Thu May 05, 2005 6:52 pm

A molecule which consists of the nitrogenous base uracil linked to the sugar ribose and which has a chain of three phosphate groups attached to the ribose in a linear fashion. UTP is required during transcription since it is a direct precursor of RNA.

I got this from OUR site's dictionary
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