Login
Answers to all your Biology Questions
|
|
ADD'P to ADPModerator: BioTeam
17 posts • Page 1 of 2 • 1, 2
ADD'P to ADP
the energy obtained from the 2nd and 3rd bond of ATP is equal. So why ATP is involved in biology rather that ADP... is ADP production is harder?
IN biology one can ask why to everything but explanations are rarely seen in regular college texts. This is why people call biology semiscience.
Actually, I believe biology's explanations are found in chemistry, whose explanations are found in physics, which seeks to explain all matter, living and non-living.
Personally, I don't know the answer, but I'm sure it has to do with chemistry. Generally speaking, the more people talk about "being saved," the further away they actually are from true salvation.
~Alex #2 Total Post Count
Well from what i know, in a hidrophobic environemnt the reaction ADP + Pi <--> ATP is reverseble, a state of chemical equilibrium. All an enzyme does is put the ADP and Pi into a hidrophobic pocket and it makes ATP. Why not ADP and AMP? Hmm... In a hidrophobic environment the reaction between ADP and AMP +Pi is not equilibrium, so i'm guessing it would have been a harder way to use it. Plus, the cyclic form of AMP and GMP evolved as secondary messagers.
Maybe not a full answer but it's all i can come up with... "As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
but is any disturbing interaction bet. cyclic and non-cyclic MPs possible there...and i didn't get why u said in hydrophobic environment the AMP+P <--->ADP isnot in equilibrium...bec. most of cytosol are hydrophilic... so did u mean hydrophilic.
ANd they aren't in equilibrium means enzymes won't be able to give us one of those... so... hrushikesh hrushikesh
No i meant hydrophobic. All an ATP synthase does is place the ADP and Pi in a hidrophobic pocket. So, it is easy easier to obtain ATP from ADP rather than ADP from AMP, since for the latter you would need some other kind of mechanism. It's easier to do it this way. My opinion, of course...
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
If equilibrium doesn't exist then the reaction will run at one direction...means that it not reversible.
example: 1. ATP <=> ADP + Pi 2. ATP ==> ADP + Pi Which one do you prefer?? of course you don't want eat a plate of ATP as your breakfast aren't you??  Q: Why are chemists great for solving problems?
A: They have all the solutions.
@numbers
Of course it can. Most enzymes work this way. What i said wasn't that it is not possible, i was thinking at the problem from an evolution point of view. It is easier to put the reactants in a hidrophobic pocket and let the reaction run for itself rather than help reactants react. Furthermore, with me reading signal transduction lately, i realised another thing: if you were to use ADP and AMP instead of ATP and ADP the following problem would arise. When you have a signal transduction pathway that uses cAMP and it is turned off, you have to "recycle" all that cAMP. this is done by an enzyme named phosphodiesterase, that turns cAMP into regular AMP. However, this would be a catastory if the cell would be using ADP-AMP. All that generated AMP would act as an alosteical activator for enzymes in cellular respiration, generating energy that, at that point, wasn't needed, therefore creating an unbalance in the cell... So, in order for the cell to use ADP-AMP instead of ATP-ADP it would have to fundamentaly alter a lot of signal transduction pathways... O course, ATP evolved way before cell comunication, but i am just saying that this path of evolution gave the cell some advantages... "As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
thanks, the enzyme thing is quite clearer now...
so the two systems i.e. ADP as currency and the cAMP pathway in its present form cannot exist togather... BUt still as you have already meantioned the evolutionary sequence matters events also matters... the present compatibility can be used to tell 'why cAMP was use was possible in such a way'...but not 'why ADP wasn't used as energy currency'... Victor- If equilibrium doesn't exist then the reaction will run at one direction...means that it not reversible. example: 1. ATP <=> ADP + Pi 2. ATP ==> ADP + Pi Which one do you prefer?? of course you don't want eat a plate of ATP as your breakfast aren't you?? BTW, what does ATP taste like
17 posts • Page 1 of 2 • 1, 2
Who is onlineUsers browsing this forum: No registered users and 0 guests |
© Biology-Online.org. All Rights Reserved. Register | Login | About Us | Contact Us | Link to Us | Disclaimer & Privacy