Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures in the field.
Proteoglycans = polymer combination of glycogen and protein...as far as I know, it's used to build the cell wall of bacteria..
Q: Why are chemists great for solving problems?
A: They have all the solutions.
I have just got this figure, about how insulin effects on glucose transport. I want to share it with you all here If you found it is too complicated for you, please don't sigh, continue to understand or just ignore it. I also try hard to read it
1. Insulin causes receptor autophosphorylation
2. Activated insulin receptor phosphorylates IRS-1
3. Phosphorylated IRS-1 activates PI-3 kinase
4. PI-3 kinase converts PIP2 => PIP3 (activates PDK1)
5. PDK1 activates protein kinase B (PKB)
6. PKB stimulates GLUT-4 translocation
Some events take place on the membrane surface, because the lipid messengers are not soluble in water. Use the back button to return to the main document.
IRS-1 = insulin receptor substrate 1
PDK1 = 3-phosphoinositide dependent kinase 1
PI-3K = phosphatidylinositol 3 kinase
PIP2 = phosphatidylinositol 4,5 bisphosphate
PIP3 = phosphatidylinositol 3,4,5 trisphosphate
PKB =protein kinase B
I think the author forgot some arrows...
Who is online
Users browsing this forum: No registered users and 2 guests