COMPLIMENTATION TEST

[SHEKHAR]

HOW CAN WE DETERMINE the cis-mutation & trans-mutation USING COMPLEMENTATION TEST?


thank u in advance for clues
shekhar
P.G.(BIOCHEM.)

[Jessieh04]

two mutants are crossed, and the F1 is analyzed. If th e F1 expresses the wild type phenotype, we conclude each mutation is in one of two possible genes necessary for the wild type phenotype. When it is shown that shown genetically that two (or more) genes control a phenotype, the genes are said to form a complementation group. Alternatively, if the F1 does not express the wild type phenotype, but rather a mutant phenotype, we conclude that both mutations occur in the same gene (cis)

Complementation tests allow us to see whether any given gene complements a mutant or fails to do so. If complementation occurs, the mutant must be in some other gene. If complementation fails to occur, the mutant is in the same gene.

[SHEKHAR]

THANKS JESSIEH.......... FOR UR COMMENTS .
IT WOULD HELP ME A LOT FOR MY STUDIES.
CAN U GIVE UR E-MAIL TO MY ID
[email protected]
I WOULD WAIT FOR UR RSPONCE
THANKS AGAIN