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dna polymerase

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dna polymerase

Postby mihir » Wed Sep 23, 2015 8:51 pm

Why has nature created dna polymerase such that it cannot initiate chain replication!?
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Re: dna polymerase

Postby claudepa » Tue Nov 03, 2015 4:27 pm

Hi. We have a tendency to give DNA polymerase a special status because it is the enzyme replicating DNA. It was also the first enzyme of replication, discovered by Arthur Kornberg. However like major functions in the cells replication is assumed by nanomachines composed of many proteins working together (replisomes?). Initiation is performed by primases which are specialized for this. One could also ask also why primers are RNA and not DNA ? Is it because the initial biological world was RNA working both as an enzyme and information storage ? Then DNA appeared as a special tool to store information ?
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Postby fanbrits » Mon Jan 18, 2016 1:29 pm

Initiation is performed by primases which are specialized for this. One could also ask also why primers are RNA and not DNA ?
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Postby Fornita » Wed Jun 01, 2016 2:55 am

If dna polymerase could initiate chain replication by itself, it will be a mess situation.
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Postby RyanShelling » Sat Jun 25, 2016 6:06 am

DNA polymerase cannot initiate chain replication by itself though... so it's not even a mess to deal with
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Postby leesajohnson » Tue Sep 06, 2016 7:12 am

DNA polymerase (DNAP) is a type of enzyme that is responsible for forming new copies of DNA, in the form of nucleic acid molecules. Nucleic acids are polymers, which are large molecules made up of smaller, repeating units that are chemically connected to one another. DNA is composed of repeating units called nucleotides or nucleotide bases. DNA polymerase is responsible for the process of DNA replication, during which a double-stranded DNA molecule is copied into two identical DNA molecules.
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