Dengue Virus

[Ana]

Hi,

Please help me asap. It is important. How does the dengue virus cause the symptoms? I know the symptoms are hemorrhaging, aches on the joints, etc, but I wish to know how does virus cause all these. Is it the proteins that the virus produces, or some other things that the virus did?

Thank you,
Ana

[victor]

Well, all the symptoms that're caused by viruses is because of their capsule protein which are synthesized during replication.
Um, can you tell me what type of virus is Dengue? is it DNA or RNA type?

[Ana]

I think its genetic material is RNA

[canalon]

A good start from a quick overview...
http://www.lehigh.edu/~kada/Dengue%20Virus%20Home.html

Hope this helps

Patrick

[victor]

Hey, I've gotten some of its characteristics.. (it's for Dengue virus)
Class: Arbovirus (arthropod-borne virus)
Familia: Flaviviridae
genus: Flavivirus
Diameter: 45-60 nm
Genome: positive-sense RNA (I think it means virulent), single stranded
virus envelope: it contains of 2 glycoproteins
Replication site: cytoplasm
Maturation site: cell transport site (Endoplasmic Reticulum)

This kind of Arbovirus has a hemaglutinogenic characteristic, so this virus can do a hemaglutination. How to inactivate it? well, this virus can be inactivated with certain conditions such as: acidic environment, high temperature, detergent and because this virus is enveloped, of course it's not resistant with ether..

Hope this helps you
Victor

[Ana]

WOW!!

Victor, you really gone into such research, and you even characterised them!

Thank you for all the information

Regards,
Ana

[victor]

Thanks to my bio book that had given me such information..oh one more thing..it's a correction for positive-sense RNA.
The meaning of +sense RNA is: viruses with this kind of RNA can use their RNA as mRNA to translate some specific proteins they need...