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Relationship between cell lines and cancer research (IHC)

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Relationship between cell lines and cancer research (IHC)

Postby wptmdoorn » Tue Aug 27, 2013 11:39 am

Please correct me if I posted my question in the wrong section.

At my current internship I am going to stain different cell lines (examples: HELAp2, COLO741, etc) with antigens (immunohistochemistry) relating to cancer research (examples p53, MSH-2/6, MLH-1, PMS-2). But I can’t seem to understand the underlying reason why we would want to build a database with those cell lines. The idea is to test lots of different cell lines with those 5 stains and record them into a database. Is it to predict further results with cancer research? Could anybody please point me in some way? I am not getting the complete picture.

Thank you very much in advance.

Regards,

William van Doorn
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Postby JackBean » Tue Aug 27, 2013 12:44 pm

Maybe best idea would be to ask your advisor. My guess would be identification of markers.
http://www.biolib.cz/en/main/

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Re:

Postby wptmdoorn » Tue Aug 27, 2013 12:58 pm

JackBean wrote:Maybe best idea would be to ask your advisor. My guess would be identification of markers.

I could. But that's the easiest way to go and I have no reason to do it like that. There should be a good idea behind it where I can find lots of information on scientific articles. I really need to push my self study into the right direction.
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