How does cancer get inherited...in cell level?

[Chiabete]

Hey,

Firstly, forgive me for my probably indecent English.

I was reading about how cancer evolves in a cell and that cancer can become inherited. I need a little brainstroming here so I can understand how this actually happens. So the germline cells that produce sex cells ( ? ) gets the effects of carcinogens/radiation causing there to be mutations in them..so what actually happens that the effect of the mutation gets inherited? In a human. So human A gets radiation in her ovaries? Causing the germline cells to start producing mutated sex cells? But aren't the eggs already been "evolved to the finest" when human A was just a thing in her mothers belly?

I'm so confused and not sure where I went wrong.


>.< I feel like I am doing a terrible job trying to explain what I need to know..but I hope someone gets what I'm trying to ask ><

[Chiabete]

Cell level is a wrong word to use....gene level is more better.

[JackBean]

First, there is difference between cancer and mutation (which may lead to cancer).

What you probably mean, is that the DNA in egg/sperm changes after some treatment (chemical, irradiation) and this mutation is transferred to offspring.

[Chiabete]

Yes, well if you say it like that it makes more sense. So there's an egg/sperm cell and in it happens a mutation that leads to cancer..and it gets inherited..so if this persons has a child it will have a mutation in the DNA and the child might get cancer from that, and the childs child aswell.

Ok, so if this is the case, thank you for clarifying!