Login

Join for Free!
119273 members


Kinases

Discussion of all aspects of cellular structure, physiology and communication.

Moderator: BioTeam

Kinases

Postby x555 » Sat Sep 22, 2012 9:57 am

I'm thinking about this question regarding kinases and I'm not sure if I have the right answer. What do kinases use as an energy source? Is the answer ATP?
x555
Garter
Garter
 
Posts: 5
Joined: Sat Sep 22, 2012 9:48 am

Re: Kinases

Postby jonmoulton » Mon Sep 24, 2012 3:13 pm

You can think of an ATP as an ADP and a phosphate bound together. It is the bond between the ADP moiety and the phosphate moiety that is the highest-energy bond in the molecule. If the terminal phosphate of ATP is transferred to a protein (releasing free ADP) then the system is in a lower-energy state that was the initial ATP and un-phosphorylated protein. That release of energy helps drive the reaction to the ADP & phosphoprotein side.

Not every kinase will use ATP as a substrate. Other high-energy phosphates are available in cells and there are many kinases.

http://en.wikipedia.org/wiki/Kinase
User avatar
jonmoulton
Viper
Viper
 
Posts: 434
Joined: Fri Feb 15, 2008 5:38 pm
Location: Philomath, Oregon, USA

Postby x555 » Tue Sep 25, 2012 9:18 am

Thank you very much!
x555
Garter
Garter
 
Posts: 5
Joined: Sat Sep 22, 2012 9:48 am



Return to Cell Biology

Who is online

Users browsing this forum: No registered users and 3 guests