Biology-Online • View topic - Female XX genotype gives advantage for genetic disorders?
Login

Join for Free!
121907 members
Advertisement
Advertisement

Female XX genotype gives advantage for genetic disorders?

Discussion of all aspects of cellular structure, physiology and communication.

Moderator: BioTeam

Female XX genotype gives advantage for genetic disorders?

Postby SysBio » Fri Jan 27, 2012 9:03 pm

Hello,

I have read that since females have an XX genotype, they have an advantage over males' XY genotype for some genetic disorders.

If the female has a recessive allele on one X chromosome it may be covered by a dominant allele on the other X chromosome....but in males, any recessive allele on the X chromosome would be expressed.

But, I also read that in females, one of the X chromosomes becomes deactivated into a BARR BODY

How does a female have any genetic advantage if one of the X chromosomes becomes deactivated into a Barr Body?
SysBio
Garter
Garter
 
Posts: 11
Joined: Tue Jan 22, 2008 11:57 am

Postby JackBean » Tue Jan 31, 2012 3:54 pm

My guess would be because it is not deactivated uniquely and uniformly throughout the body
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.
User avatar
JackBean
Inland Taipan
Inland Taipan
 
Posts: 5694
Joined: Mon Sep 14, 2009 7:12 pm


Return to Cell Biology

Who is online

Users browsing this forum: No registered users and 1 guest