Login

Join for Free!
112218 members


Membrane proteins

Discussion of all aspects of cellular structure, physiology and communication.

Moderator: BioTeam

Membrane proteins

Postby poroto » Wed Mar 09, 2011 12:51 pm

Dear All,

I am doing some literature search, trying to find a biological system that is similar to a purely physical
system that I am working on. As a physicist, I am a bit lost in terms of the sources to consult!

I am trying to find information of a hypothetical membrane protein, basically to see if something like it
does actually exists. The protein would be a hollow capsule containing a tethered polymer chain inside,
that is released, for example to anchor to a substrate or for recognition purposes.

I would be thrilled if someone can point in me the right direction to look for it!

Best,

Poroto
poroto
Garter
Garter
 
Posts: 1
Joined: Wed Mar 09, 2011 12:44 pm

Re: Membrane proteins

Postby protold » Mon Mar 14, 2011 7:14 am

Hola, I don´t know if this could be that you search. Look in google images about protein G coupled receptors or chemokine receptors. These are transmembrane proteins with areas in both sides in that the union of ligand in the external side promotes a conformotioal change which actives the internal side. Sorry if I don´t give you more details, but i would have to refresh my concepts. Buena suerte
protold
Garter
Garter
 
Posts: 23
Joined: Thu Oct 14, 2010 6:34 am

Postby JackBean » Mon Mar 28, 2011 7:34 am

poroto: I think you're looking rather for something like sodium channel, which has a plug closing the channel after prolonged functioning. Thus, it does actually the opposite, what you probably want, but it could work as a model for you ;)
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.
User avatar
JackBean
Inland Taipan
Inland Taipan
 
Posts: 5652
Joined: Mon Sep 14, 2009 7:12 pm


Membrane proteins:Location, quantitative specification

Postby olgaka » Sun Apr 03, 2011 8:55 am

Hi friends, I am new here. Could anyone name the methods for the location of membrane proteins and their quantitative specification?
olgaka
Garter
Garter
 
Posts: 1
Joined: Sun Apr 03, 2011 8:49 am

Postby JackBean » Sun Apr 03, 2011 10:09 am

you mean probably methods for determination of protein localization, rigth? Some of them are:
imunodetection with electron microscope
activity staining with optical microscope
fluorescent protein tags
colocalization with other proteins (but that's basically the previous)
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.
User avatar
JackBean
Inland Taipan
Inland Taipan
 
Posts: 5652
Joined: Mon Sep 14, 2009 7:12 pm


Return to Cell Biology

Who is online

Users browsing this forum: No registered users and 1 guest

cron