Login

Join for Free!
114561 members


Where is embryonic stem cell research at?

Debate and discussion of any biological questions not pertaining to a particular topic.

Moderator: BioTeam

Where is embryonic stem cell research at?

Postby qlidnaque » Mon Feb 07, 2011 3:46 am

Where is embryonic stem cell research at compared to adult stem cell research? I believe both should be pursued equally as they yield different benefits, but at the moment, I have not seen too many success stories using embryonic stem cells. I understand the development of it may have been hampered due to unreasonable political bans, so was wondering if we still have to way a few more years before embryonic stem cell research starts blooming. And stem cells in general, when do you guys think it would be possible to start having human clinical trials of artificially grown stem cell organs for major organs such as heart, liver, or lungs?

And as a side question, I'm wondering where exactly you get embryonic stem cells from if your an adult male? Isn't all that's left of me adult cells? Especially since I haven't made investments to preserve my mother's umbilical cords at birth. Or can I inject my DNA into other people's embryonic cells with the nucleus removed?
qlidnaque
Garter
Garter
 
Posts: 2
Joined: Mon Feb 07, 2011 3:37 am

Postby Kezzer » Mon Feb 07, 2011 8:06 pm

Hey a general prediction of when we can expect mainstream stem cell therapy has been placed as being between 10-20 years away, the science is still very much in its infancy due to not only restrictions placed on research but also the complexity.

As far as it goes on how you get stem cells as an adult, the somatic cells can be reprogrammed to behave as if they are pluripotent. Look up about somatic cell nuclear transfer (SCNT) which has potential use in therapeutic cloning.
BSc (Hons) Forensic Science,
MSc Biological Sciences
User avatar
Kezzer
Garter
Garter
 
Posts: 31
Joined: Thu Nov 25, 2010 7:20 pm

Postby Darby » Tue Feb 08, 2011 2:10 pm

They are a long way from solving the one big problem: once differentiated, embryonic stem cells are foreign to the host, like any donor tissue (as stem cells, they don't show enough antigens to be "foreign'). Converting cells from an adult to stem cells avoids that, so it's likely that the future of medical applications is there.

We wouldn't be there, of course, without the earlier embryonic work.
Darby
Viper
Viper
 
Posts: 1262
Joined: Thu Mar 02, 2006 5:29 pm
Location: New York, USA


Postby Kezzer » Fri Feb 11, 2011 3:29 pm

Exactly although therapeutic methodology has already been developed, SCNT. The patient is the donor of the cell as so there is no rejection....the restrictions in the case of SCNT are the fact that human eggs are required and ennucleated ready for nuclear transfer. There is talk of developing artifical "eggs" for this purpose so that human eggs are not required to prevent talk of prevention/destruction of potential life but obviously to get something artifical to behave in the same way as a human egg would take a huge amount of work! I doubt that SCNT would become commercialised if human eggs were used and so this is the major block for the technology!
BSc (Hons) Forensic Science,
MSc Biological Sciences
User avatar
Kezzer
Garter
Garter
 
Posts: 31
Joined: Thu Nov 25, 2010 7:20 pm

Re: Where is embryonic stem cell research at?

Postby qlidnaque » Mon Sep 12, 2011 10:20 pm

What about in countries where stem cell research laws are much more open, do you guys still think it won't happen? (as in treatment using embryonic eggs)
qlidnaque
Garter
Garter
 
Posts: 2
Joined: Mon Feb 07, 2011 3:37 am


Return to General Discussion

Who is online

Users browsing this forum: No registered users and 7 guests

cron