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a question on gentic fiddling as it were

Genetics as it applies to evolution, molecular biology, and medical aspects.

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a question on gentic fiddling as it were

Postby declan5584 » Fri Jan 21, 2011 1:37 pm

This may come across as an odd question but hey,
would it be possible to take the genetic material from a sperm cell, remove the genetic material from that of an egg and replace it with that of the sperm, and then fertilise that egg that has the sperms DNA in it with another sperm from a different person, I have looked around a bit and no one seems to be able to give a straight answer, even my teacher was unsure
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Postby Darby » Fri Jan 21, 2011 6:18 pm

It would be feasible, but the chromosomes would all have male imprints (a particular type of methylation) and I don't know if you'd get something viable. Some recent work indicates that only the maternal chromosomes get used in the earliest developmental stages, so maybe nothing would happen.
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Postby JackBean » Sat Jan 22, 2011 9:58 pm

what about the sex chromosomes?

Darby: I think there is some reset before fertilization, so that should be sufficient ;)

Cis or trans? That's what matters.
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Re: a question on gentic fiddling as it were

Postby skeptic » Sat Jan 22, 2011 11:19 pm

Darby is correct.
Short answer is no. Fertilisation is more complex than the simple picture given, and many other factors have to be right.
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