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HELP! translate the piece of mRNA

Genetics as it applies to evolution, molecular biology, and medical aspects.

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HELP! translate the piece of mRNA

Postby ola80 » Wed Dec 01, 2010 2:27 pm

Please help me with this question, How does it work?
Translate the following piece of mRNA

1) CGAAUGCCAGCAGGCUCCCCUCAU
describe the effect of changing the second base in the third codon from a C to a U.
What effect might this have on the protein?
THANKS FOR HELP!
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Re: HELP! translate the piece of mRNA

Postby JackBean » Wed Dec 01, 2010 3:01 pm

your sequence: CGAAUGCCAGCAGGCUCCCCUCAU

first, find the START codon (ATG for DNA): CGA AUG CCAGCAGGCUCCCCUCAU

now, divide the triplets: CGA AUG CCA GCA GGC UCC CCU CAU

asign amino acid to each triplet up to any STOP codon in frame. Choose any table you like from the pictures http://lmgtfy.com/?q=genetic+code

now, the third codon is CGA AUG CCA GCA GGC UCC CCU CAU so just change the C to U and look, whether it changes the amino acid coded.

that's all ;)
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.
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Re: HELP! translate the piece of mRNA

Postby ola80 » Wed Dec 01, 2010 4:23 pm

thanks! but why GCA is the third codon? it looks like fourth, but i start to count from the start codone, I mean AUG ? and in this sequence :
CGAAUGCCAGCAGGCUCCCCUCAU i was looking for the stop codon but there's no STOP codon, am i right? - STOP codon are: UAA,UAG,UGA
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Postby JackBean » Thu Dec 02, 2010 2:16 pm

start calculating from the START codon ;)

Yes, you're rigth, there's no STOP codon...
http://www.biolib.cz/en/main/

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