Dynactin...definition not in dictionary. Anyone know?

[sundew773]

I have a question that asks to compare dynein to dynactin, but I can't really understand what dynactin is...

[James]

'Dynein and dynactin are required for vesicular trafficking, mitotic spindle assembly, and development of polarity.' I know no more.

[duwende]

Dude awesome question. I think you're in my cell bio class for the summer. I googled dynactin for the study guide and this was the first link. Lol.

[duwende]

"Dynein activator complex that stimulates vesicle transport. Includes dynactin (160 kD) and polypeptides of 62, 50, 45, 37, and 32, the 45 kD (possibly actin-RPV) being the most abundant. All the subunits co-sediment with antibody to dynactin 160 and the complex behaves as a stable 20S multiprotein assembly. See centractin."

Possibly that helps?

[sundew773]

Thank you! Are you taking cell bio at UT? Because then I am in your class...and if so, good luck on the final tomorrow

[Dr.Stein]

Dynein, dynactin are contractile protein, as well as actin and myosin on skeletal muscle, that play a role in spermatozoa motility.