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NADH and FADH2

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NADH and FADH2

Postby victor » Wed Jun 22, 2005 8:05 am

NADH and FADH2 give electron and H+ to start ETS. My question is how many ATP will be formed from ETS for each NADH and FADH2??
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Postby Jelanen » Wed Jun 22, 2005 3:22 pm

Use the search function!!!! This kind of stuff has been hashed, rehashed and recycled hashed.

http://www.biology-online.org/biology-forum/viewtopic.php?t=582&highlight=fadh+nadh

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Postby Dr.Stein » Thu Jul 07, 2005 2:55 pm

1 NADH will generates 3 ATPs
1 FADH2 will generates 2 ATPs

Jelanen: You can merge similar topics or close one of them to reduce tons of topic in this board. Just a little suggestion, because I also a moderator of a forum of something else :wink:
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Postby victor » Sun Jul 10, 2005 1:41 pm

I read the biochem book and have it checked again and again...it said that aerobic respiration generates 36 ATP per glucose molecule...and if we count again:
Glycolysis = 2 ATP and 2 NADH
Oxydative decarbocilation = 2 NADH
Krebs = 6 NADH, 2 FADH2, 2 ATP (or can be GTP based on body necessity)
ETS = changes NADH and FADH2 into ATP

We see that there're 10 NADH, 2 FADH2 and 4 ATP.
Then the result will be 38 ATPs...but the book said that there're only 36 ATPs per glucose molecule...how can?? (if we make ATP in Krebs are involved because the book wrote it ATP not GTP)
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Postby Poison » Sun Jul 10, 2005 6:25 pm

We either say 36 or 38 ATP. Depending on the pathway used. These are the 2 pathways: Malate Dehydrogenase, Glycerol-Phosphate Dehydrogenase.
This is the point:
Glycolysis = 2 ATP and 2 NADH

Let me explain it to you roughly. That 2 NADH (formed during glycolysis) give their H to the either NAD or FAD which is present in the mitochondria. (means that those NADH are not used directly.) If they give their H to FAD, present in the mitochondria, a total of 36 ATP is produced, if they give it to NAD a total of 38 ATP is produced.
Hope this helped. :)
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Postby victor » Mon Jul 11, 2005 11:46 am

Usually my book use a malate dehydrogenase pathway in the Krebs cycle..so, I've just known that there're 2 pathways...thanks Ozge.. :lol:
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Postby Poison » Mon Jul 11, 2005 5:35 pm

You're welcome. :)
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Postby Dr.Stein » Tue Jul 12, 2005 3:37 am

Different cells will generate different amount of ATP. Some cells can generate 36 ATP whereas another cells generate 38 ATP depends on the type of cells and their activities. For instance muscle cells generate 38 ATP, gland cells only 36 ATP.
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Postby victor » Wed Sep 21, 2005 11:42 am

Dr.Stein wrote:Different cells will generate different amount of ATP. Some cells can generate 36 ATP whereas another cells generate 38 ATP depends on the type of cells and their activities. For instance muscle cells generate 38 ATP, gland cells only 36 ATP.


I've read in some books and they said that the difference between 36 ATP and 38 ATP is based on the prokaryotic and Eukaryotic cell. Eukaryotic cell produced 36 ATP because in the Glycolysis, 4H+ is taken by protein carrier named 2 NAD+ to form NADH+H to the ETS. But, during the way from Cytoplasm to mitochondrion cristae, NADH+H is converted into FADH2 and get processed just the same like other FADH2.
so: Glycolysis = 2 ATP (net) + 2 FADH2
Krebs = 2 ATP + 8 [NADH+H] + 2 FADH2
Total NADH+H = 8 x 3 ATP = 24 ATP
Total FADH2 = 4 x 2 ATP = 8 ATP
Others = 4 ATP = 4 ATP
whole ATP from 1 molecule Glucose = 36 ATP

While in prokaryotic cell, NADH+H doesn't converted into FADH2 durinf transport..so, they produce 38 ATP.

That's what I read
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Postby sdekivit » Thu Sep 22, 2005 4:13 pm

Dr.Stein wrote:Different cells will generate different amount of ATP. Some cells can generate 36 ATP whereas another cells generate 38 ATP depends on the type of cells and their activities. For instance muscle cells generate 38 ATP, gland cells only 36 ATP.


it's due to the malate/aspartate shuttle.
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Postby MrMistery » Fri Sep 23, 2005 8:09 pm

@victor
I don't think so.... :D
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Postby victor » Sun Sep 25, 2005 11:52 am

Any reason Andrew??well, that's based on my bio book... :D
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