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Chromosomes

Human Anatomy, Physiology, and Medicine. Anything human!

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Chromosomes

Postby mekamitchell » Thu Nov 19, 2009 1:36 pm

Will inheriting extra or insufficient copies of each chromosome be beneficial, detrimenta, or have no effect on offspring? Why?
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Postby JackBean » Thu Nov 19, 2009 1:50 pm

Insufficient copies will be probably always detrimenta, if that means bad :lol:
Extra copies could be beneficial, if there where some good genes*), but usually that leads to various genetic disorders, like the Down syndrome. Look at these links
http://en.wikipedia.org/wiki/Genetic_disorder
http://en.wikipedia.org/wiki/List_of_genetic_disorders
:wink:

EDIT
*) and vice versa, deletion could be beneficial, if bad genes were deleted ;)
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.
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Postby kolean » Thu Nov 19, 2009 4:30 pm

It would all be detrimental, since you stated whole chromosomes. It all has to do with dosage compensation of gene products. This is why even the double X chromosomes in females has to have one of the chromosomes be inactivated, so as not to cause detrimental effects to the organism. While the only X in the male (along with the Y chromosome) is fully activated.
Balance is the key. You can not have too little of one gene product and too much of a gene product.
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Postby MrMistery » Fri Nov 20, 2009 2:40 pm

@kolean
not necessarily. Yes in humans that is the case. But for example in plants poliploidy is often seemed and it has been a beneficial thing for plants in cold climates. And if you have an organism like an ophioglossum fern which has its genome divided between around n=600 chromosomes, an extra chromosome has so few genes that it may just be beneficial in some environments.
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
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Postby kolean » Fri Nov 20, 2009 3:38 pm

True, I do seem to assume animal as the organism in question.
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Postby JackBean » Sat Nov 21, 2009 2:23 am

Yeah, people usually assume animals as all organisms...
But in this case, as is it in Human Biology, you were probably right:)
http://www.biolib.cz/en/main/

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