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Apoptosis?

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Apoptosis?

Postby Rinta » Tue Jun 28, 2005 2:32 am

1. sculpting fingers and deleting tail are involved in
apoptosis.Where are these cells after doing apoptosis ?
2. Is heterophagig in apoptosis same with heterophagig in
lysosom function ?can you explain about it ?


thanks
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Postby Dr.Stein » Thu Jul 07, 2005 2:48 pm

Apoptosis is a programmed cell death. It is initialized by DNA degradation. Since there is no coordination within the cell, because of the nuclues degeneration, the cell will die. The debris then will be cleared by macrophages. In apoptosis, the cell 'decided to commit suicide' without making any damage to their surrounding. This will avoid lysosomes to come out from the cell and secrete their hydrolitic enzyme, lysozyme, to damage other cells on their surrounding.

There is a another cell death named necrosis. In this case, plasma membrane burst out and then lysosome will spread over their environment, starts to digest cells, and result in tissue damage.
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Postby victor » Fri Jul 08, 2005 8:53 am

The case is like frogs' tails isn't it???at first I thought that Lysosoms take part because lysosoms are phagocytic cell's organel...
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Postby Dr.Stein » Sun Jul 10, 2005 10:50 am

What do you mean by "phagocytic cell's organel"? As I said, lysosoms contain hydrolytic enzyme that will digest anything on the surround when it spreads out. Lysosoms do not eat the cell :wink:
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